Irinotecan Related Compound D – (R)-9-[(1,4’Bipiperidine)-1’carboxyl]-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin hydrochloride, trihydrate